Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853324 | 0.89 | FFAR4 (0.51) | FFAR4CD274FFAR1MRGPRX4 | |
| SCHEMBL10852512 | 0.82 | FFAR4 (0.45) | FFAR4CD274FFAR1CSF1RMRGPRX4 | |
| SCHEMBL11153474 | 0.82 | ALDH1A1 (0.53) | — | |
| SCHEMBL9579195 | 0.80 | AGTR1 (0.43) | FFAR4FFAR1 | |
| SCHEMBL11096066 | 0.79 | TP53 (0.57) | — | |
| SCHEMBL11111968 | 0.78 | FFAR4 (0.45) | FFAR4CD274FFAR1CSF1RMRGPRX4 | |
| SCHEMBL10227 | 0.77 | CACNA1G (0.46) | — | |
| SCHEMBL10849715 | 0.76 | AGTR1 (0.41) | — | |
| SCHEMBL11163236 | 0.75 | ALDH1A1 (0.60) | — | |
| SCHEMBL14573028 | 0.74 | FFAR4 (0.67) | FFAR4FFAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582847-A | 4-chloro-2-phenylimidazole-5-acetic acid derivatives and use as diuretics and hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| EP-0103647-A1 | 4-CHLORO-2-PHENYLIMIDAZOLE-5-ACETIC ACID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1984-03-28 | — | — | EP | disclosed |