Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852512 | 0.86 | FFAR4 (0.45) | FFAR4FFAR1CSF1RSMN1; SMN2ALDH1A1 | |
| SCHEMBL10852592 | 0.78 | FFAR4 (0.46) | FFAR4FFAR1CSF1RMRGPRX4CD274 | |
| SCHEMBL10853324 | 0.78 | FFAR4 (0.51) | FFAR4FFAR1MRGPRX4CD274PTGER1 | |
| SCHEMBL4704085 | 0.71 | FFAR4 (0.63) | FFAR4FFAR1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL8126133 | 0.70 | AR (0.51) | ALDH1A1RAB9ALMNANPC1MAPT | |
| SCHEMBL3872301 | 0.70 | MAPT (0.51) | FFAR4SMN1; SMN2RAB9AL3MBTL1LMNA | |
| SCHEMBL9579195 | 0.69 | AGTR1 (0.43) | FFAR4FFAR1MAPTKMT2AMEN1 | |
| SCHEMBL980151 | 0.68 | MAOA (0.56) | FFAR4SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL10852995 | 0.68 | FFAR4 (0.62) | FFAR4FFAR1SMN1; SMN2L3MBTL1MRGPRX4 | |
| SCHEMBL13144443 | 0.66 | MRGPRX4 (0.68) | FFAR4FFAR1RAB9AL3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103647-A1 | 4-CHLORO-2-PHENYLIMIDAZOLE-5-ACETIC ACID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1984-03-28 | — | — | EP | disclosed |