Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.64 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852018 | 0.88 | HTR1A (0.50) | CHIACHIT1LTA4HDRD3KCNA5 | |
| SCHEMBL11199379 | 0.81 | HTR1A (0.59) | DRD3HTR1A | |
| SCHEMBL16826340 | 0.81 | CHIA (0.67) | CHIACHIT1LTA4HPTGS2TSHR | |
| SCHEMBL10856395 | 0.81 | HTR1A (0.54) | DRD3HTR1A | |
| SCHEMBL16825716 | 0.77 | CHIA (0.62) | CHIACHIT1LTA4HPTGS2TSHR | |
| SCHEMBL4120225 | 0.72 | RAB9A (0.69) | CHIACHIT1LTA4HPTGS2TSHR | |
| SCHEMBL16846162 | 0.72 | CHIT1 (0.60) | CHIACHIT1LTA4HPTGS2TSHR | |
| SCHEMBL16825946 | 0.72 | CHIA (0.66) | CHIACHIT1LTA4HPTGS2TSHR | |
| SCHEMBL229697 | 0.72 | LTA4H (0.90) | LTA4HPTGS2TSHRATML3MBTL1 | |
| SCHEMBL10857813 | 0.71 | LTA4H (0.67) | CHIACHIT1LTA4HPTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582833-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-04-15 | — | — | US | disclosed |