Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.48 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199379 | 0.94 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL10856395 | 0.93 | HTR1A (0.54) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL10852847 | 0.88 | CHIA (0.64) | HTR1ADRD3CHIT1CHIALTA4H | |
| SCHEMBL11205135 | 0.80 | HTR1A (0.55) | HTR1ADRD2DRD3SIGMAR1 | |
| SCHEMBL16825744 | 0.80 | CHIT1 (0.51) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL11203954 | 0.78 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL10856538 | 0.77 | GAA (0.58) | SIGMAR1 | |
| SCHEMBL16826405 | 0.73 | DRD2 (0.59) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL1307349 | 0.73 | LTA4H (0.63) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL16825679 | 0.72 | HTR1A (0.54) | HTR1ADRD2HTR2ADRD3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582833-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-04-15 | — | — | US | disclosed |