Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548578 | 0.85 | IDO1 (0.51) | MTNR1AMTNR1BNPC1RAB9AGAA | |
| SCHEMBL14277764 | 0.78 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL28598895 | 0.77 | ALDH1A1 (0.44) | MTNR1AMTNR1BRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19869139 | 0.74 | LMNA (0.49) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23051110 | 0.73 | HTT (0.47) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1395738 | 0.71 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL18211081 | 0.71 | CYP1A2 (0.45) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2095490 | 0.70 | TAAR1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10862913 | 0.70 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL12317734 | 0.70 | ALDH1A1 (0.46) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592307-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-20080279922-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2008-11-13 | — | — | US | disclosed |
| US-7238368-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279922-A1 | Releasable linkage and compositions containing same | CD44, SHMT1, HCAR1 | MTNR1A 3064/4885MTNR1B 2717/4885NPC1 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.