Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.64 |
| ▸ | HRH1 | P35367 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375133 | 0.82 | THRA (0.56) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL1332021 | 0.81 | KCNH2 (0.64) | DRD2TMEM97SIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL14376070 | 0.81 | HTR2A (0.51) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL2094771 | 0.80 | KCNH2 (0.50) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL5178875 | 0.77 | KCNH2 (0.57) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL28481556 | 0.77 | DRD2 (0.68) | DRD2DRD3SIGMAR1SMN1; SMN2 | |
| SCHEMBL18483417 | 0.77 | LTA4H (0.66) | SLC6A3LTA4HLMNAMAPK1HTT | |
| SCHEMBL10648046 | 0.77 | KCNH2 (0.53) | DRD2SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9537160 | 0.77 | DRD2 (0.51) | DRD2DRD3HTR1AHTR2ASLC6A2 | |
| SCHEMBL11241598 | 0.76 | DRD2 (0.68) | DRD2DRD3HTR1AHTR2ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167355-A2 | Thiazolidine derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1986-01-08 | — | — | EP | disclosed |