Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865823 | 0.82 | GRIN1 (0.40) | HRH3MAOB | |
| SCHEMBL10600866 | 0.74 | PTGDR2 (0.44) | S1PR5ESR1ESR2DRD1DRD2 | |
| SCHEMBL9157251 | 0.72 | YAP1 (0.44) | S1PR5DRD1DRD2 | |
| SCHEMBL9162086 | 0.64 | DRD1 (0.52) | DRD1DRD2 | |
| SCHEMBL9158330 | 0.63 | DRD1 (0.74) | SMN1; SMN2DRD1DRD2 | |
| SCHEMBL5871291 | 0.62 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16937202 | 0.60 | OPRM1 (0.53) | RAB9ATP53SMN1; SMN2MAOBKCNH2 | |
| SCHEMBL8408576 | 0.59 | LMNA (0.54) | TP53MAOB | |
| SCHEMBL8408574 | 0.58 | LMNA (0.61) | RAB9AS1PR5TP53SMN1; SMN2MAOB | |
| SCHEMBL27037680 | 0.58 | MRGPRX4 (0.57) | NPC1RAB9AHRH3TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167204-A1 | Method for improving the absorption and effectiveness of a catecholamine compound | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1986-01-08 | — | — | EP | disclosed |