Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10867944 | 0.99 | HTR1A (0.53) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| SCHEMBL10871232 | 0.94 | HTR2A (0.50) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL10867806 | 0.93 | HTR2A (0.49) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| SCHEMBL10867780 | 0.88 | KMT2A (0.50) | DRD2DRD3 | |
| SCHEMBL10866968 | 0.85 | HTR2A (0.50) | HTR1ADRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL10867337 | 0.84 | SMN1; SMN2 (0.47) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| SCHEMBL10867950 | 0.83 | HTR2A (0.49) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| SCHEMBL10868207 | 0.81 | MPO (0.54) | HTR1ASLC6A4HTR7 | |
| SCHEMBL10866988 | 0.81 | HTR2A (0.59) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL10868996 | 0.81 | MTNR1A (0.49) | HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | claimed |