Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10867806 | 0.99 | HTR2A (0.49) | HTR2AHDAC8HDAC6DRD2DRD3 | |
| SCHEMBL10867065 | 0.94 | HTR1A (0.54) | HTR2ADRD2DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL10867944 | 0.93 | HTR1A (0.53) | HTR2ADRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL10866968 | 0.91 | HTR2A (0.50) | HTR2AHDAC8HDAC6DRD2DRD3 | |
| SCHEMBL10867780 | 0.90 | KMT2A (0.50) | DRD2DRD3MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL10867337 | 0.89 | SMN1; SMN2 (0.47) | HTR2AHDAC8HDAC6DRD2DRD3 | |
| SCHEMBL10867950 | 0.89 | HTR2A (0.49) | HTR2AHDAC8HDAC6DRD2DRD3 | |
| SCHEMBL10868996 | 0.87 | MTNR1A (0.49) | HTR2AHTR1ATSHR | |
| SCHEMBL10868207 | 0.87 | MPO (0.54) | HTR1ASLC6A4HTR7 | |
| SCHEMBL10866988 | 0.87 | HTR2A (0.59) | HTR2ADRD2HTR1ASLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | disclosed |