Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | SHBG | P04278 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079251 | 1.00 | NR3C1 (0.50) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL11240496 | 0.86 | LMNA (0.68) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL11240498 | 0.86 | LMNA (0.68) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL10868441 | 0.85 | SHBG (0.70) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL10892430 | 0.85 | SHBG (0.70) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL9128581 | 0.82 | SHBG (0.65) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL9128571 | 0.82 | SHBG (0.65) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL15079253 | 0.82 | LMNA (0.49) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL10444770 | 0.82 | LMNA (0.49) | NR3C1LMNAPGRSHBGMEN1 | |
| SCHEMBL15079258 | 0.82 | LMNA (0.49) | NR3C1LMNAPGRSHBGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402963-A2 | 17-Alpha ethynyl steroids | THE UPJOHN COMPANY (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4614621-A | Ethynylation of 16-methylene-17-keto steroids | THE UPJOHN COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| US-4588529-A | Mercury removal process | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0179496-A1 | 16-Sulfinylmethyl-steroids, their preparation and use | THE UPJOHN COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0148616-A2 | Stabilised monolithium acetylide and the ethynylation of steroids | THE UPJOHN COMPANY (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4526720-A | Process to prepare stabilized monolithium acetylide | THE UPJOHN COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |