Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455707 | 0.83 | ALOX5 (0.51) | ALOX5MGLLADRB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11210741 | 0.75 | GAA (0.45) | ALOX5ALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL5768412 | 0.66 | ALOX5 (1.00) | ALOX5MGLLADRB1ALDH1A1MAPT | |
| SCHEMBL31021926 | 0.66 | ALOX5 (1.00) | ALOX5MGLLADRB1ALDH1A1MAPT | |
| SCHEMBL8632730 | 0.65 | ALOX5 (0.50) | ALOX5MGLLADRB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10429462 | 0.64 | MAPT (0.67) | ALOX5MGLLMAPTMEN1KMT2A | |
| SCHEMBL9645814 | 0.63 | ALOX5 (1.00) | ALOX5ALOX15 | |
| SCHEMBL11133610 | 0.63 | HPGD (0.62) | MGLLALDH1A1MAPTTP53MEN1 | |
| SCHEMBL11272168 | 0.62 | MGLL (0.47) | ALOX5MGLLSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL22904557 | 0.62 | HTR1A (0.51) | ALOX5ADRB1ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173178-A2 | Unsymmetrical 1:2 chromium complex dyes | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |