SCHEMBL11272168

SCHEMBL11272168

CN1CC(=N)N(c2ccccc2Cl)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.47
BCL2A1 Q16548 1/20 0.43
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 5/20 0.39
MAPT P10636 4/20 0.39
POLB P06746 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PGR P06401 1/20 0.39
PKM P14618 1/20 0.38
RAD51 Q06609 1/20 0.38
ALOX5 P09917 2/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11272449 0.83 MGLL (0.50) MGLLBCL2A1KMT2AMEN1ALDH1A1
SCHEMBL10962949 0.81 MEN1 (0.47) MGLLKMT2AMEN1ALDH1A1POLB
SCHEMBL11037007 0.76 MGLL (0.41) MGLLKMT2AMEN1ALDH1A1NPC1
SCHEMBL9819404 0.74 MGLL (0.47) MGLLBCL2A1KMT2AMEN1ALDH1A1
SCHEMBL11270496 0.73 ELANE (0.44) MGLLKMT2AMEN1ALDH1A1MAPT
SCHEMBL11267668 0.73 KMT2A (0.49) MGLLBCL2A1KMT2AMEN1ALDH1A1
SCHEMBL10874965 0.73 KMT2A (0.47) BCL2A1KMT2AMEN1ALDH1A1MAPT
SCHEMBL11732984 0.73 SMN1; SMN2 (0.49) MGLLBCL2A1KMT2AMEN1ALDH1A1
SCHEMBL11268915 0.72 ALDH1A1 (0.54) BCL2A1KMT2AMEN1ALDH1A1MAPT
SCHEMBL11278830 0.71 TSHR (0.43) BCL2A1ALDH1A1HSD17B10TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024570-B1 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed