Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564366 | 0.81 | GAA (0.50) | MEN1KMT2ACYP1A1CYP1B1MAPT | |
| SCHEMBL10874394 | 0.81 | MAPT (0.48) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9564371 | 0.81 | GAA (0.50) | MEN1KMT2ACYP1A1CYP1B1MAPT | |
| SCHEMBL9619495 | 0.79 | MAPT (0.66) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL10264321 | 0.75 | LSS (0.56) | MEN1KMT2ATRPV1CES2CES1 | |
| SCHEMBL9564413 | 0.73 | CES2 (0.40) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL9564422 | 0.73 | CES2 (0.40) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL2692097 | 0.71 | MAPT (0.52) | MEN1KMT2ACYP1A1CYP1B1MAPT | |
| SCHEMBL9564388 | 0.71 | MAPT (0.52) | MEN1KMT2ACYP1A1CYP1B1MAPT | |
| SCHEMBL2692103 | 0.71 | MAPT (0.52) | MEN1KMT2ACYP1A1CYP1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181018-A2 | Anticoccidial isoxazoles and compositions containing them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-05-14 | — | — | EP | disclosed |