Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2121667 | 1.00 | NPSR1 (0.55) | NPSR1RAD52FAAHCNR1CNR2 | |
| SCHEMBL17244840 | 0.87 | FAAH (0.53) | FAAHDNM1CASP2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3622353 | 0.86 | L3MBTL1 (0.52) | FAAHCNR1CNR2DNM1CASP2 | |
| Hydrochloric Acid SCHEMBL10868713 | 0.85 | EPHX2 (0.50) | CNR1KDM4EMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6244706 | 0.85 | HPGD (0.54) | CNR1CNR2LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL15553396 | 0.84 | NPSR1 (0.60) | NPSR1RAD52FAAHLMNAHTT | |
| SCHEMBL21101114 | 0.83 | CASP2 (0.53) | FAAHDNM1CASP2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11597133 | 0.82 | FAAH (0.60) | FAAHHTTDNM1CASP2KDM4E | |
| Hydrochloric Acid SCHEMBL11595919 | 0.82 | FAAH (0.60) | FAAHHTTDNM1CASP2KDM4E | |
| Hydrochloric Acid SCHEMBL11595739 | 0.82 | FAAH (0.60) | FAAHHTTDNM1CASP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192145-A2 | Quaternary alkylamidobetain esters, process for their preparation and their use as laundry softening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-27 | — | — | EP | disclosed |