Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426521 | 0.86 | LTA4H (0.51) | LTA4HMAPTLMNATLR4TLR2 | |
| SCHEMBL160454 | 0.82 | LMNA (0.43) | LTA4HALDH1A1HDAC3TSHRSMN1; SMN2 | |
| SCHEMBL29161709 | 0.81 | LTA4H (0.49) | LTA4HTSHRTLR4TLR2 | |
| SCHEMBL6320373 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AGAANPSR1 | |
| SCHEMBL6052855 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTTSHRNPC1RAB9A | |
| Diphenylether SCHEMBL9334093 | 0.78 | LTA4H (0.76) | LTA4HHTTALDH1A1MAPTKMT2A | |
| SCHEMBL7704998 | 0.78 | LTA4H (0.46) | LTA4HALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL38728 | 0.77 | LMNA (0.46) | LTA4HALDH1A1MAPTHDAC3SMN1; SMN2 | |
| Diphenylether SCHEMBL11264556 | 0.76 | LTA4H (0.73) | LTA4HHTTALDH1A1MAPTKMT2A | |
| Diphenylether SCHEMBL11183529 | 0.76 | LTA4H (0.73) | LTA4HHTTALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |