Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.30 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290075 | 0.75 | POLB (0.48) | POLBNLRP3TTRABCB11TOP1 | |
| SCHEMBL10875516 | 0.75 | POLB (0.58) | POLBNLRP3TTRABCB11TOP1 | |
| SCHEMBL10874720 | 0.75 | POLB (0.48) | POLBNLRP3TTRABCB11TOP1 | |
| SCHEMBL4317657 | 0.72 | POLB (0.56) | POLBNLRP3TTRTOP1BACE1 | |
| SCHEMBL18290079 | 0.72 | POLB (0.46) | POLBNLRP3TTRTOP1BACE1 | |
| SCHEMBL22991510 | 0.70 | POLB (0.44) | POLBNLRP3TTRABCB11TOP1 | |
| SCHEMBL14136180 | 0.69 | LMNA (0.43) | POLBNLRP3ABCB11TOP1BACE1 | |
| SCHEMBL25941557 | 0.68 | POLB (0.42) | POLBNLRP3TTRTOP1BACE1 | |
| SCHEMBL6363949 | 0.67 | POLB (0.43) | POLBNLRP3ABCB11TOP1BACE1 | |
| SCHEMBL4644625 | 0.67 | POLB (0.47) | POLBNLRP3ABCB11TOP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565888-A | Substituted salicylic acid amide anthelmintics | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |