Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | CELA1 | Q9UNI1 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27426714 | 0.80 | MCL1 (0.41) | POLBNLRP3TOP1CYP3A4BACE1 | |
| SCHEMBL22991606 | 0.80 | POLB (0.39) | POLBNLRP3TOP1CYP3A4BACE1 | |
| SCHEMBL22991542 | 0.78 | POLB (0.35) | POLBNLRP3TOP1CYP3A4BACE1 | |
| SCHEMBL14136180 | 0.77 | LMNA (0.43) | POLBNLRP3TOP1BACE1HTT | |
| SCHEMBL24110787 | 0.76 | TPMT (0.47) | POLBNLRP3CYP3A4BACE1HTT | |
| SCHEMBL22991508 | 0.76 | POLB (0.36) | POLBNLRP3TOP1CYP3A4BACE1 | |
| SCHEMBL22991509 | 0.75 | POLB (0.38) | POLBNLRP3TOP1BACE1HTT | |
| SCHEMBL24106114 | 0.75 | ABCB11 (0.37) | POLBNLRP3BACE1GAAMAPT | |
| SCHEMBL24106257 | 0.74 | ABCB11 (0.43) | POLBNLRP3TOP1CYP3A4BACE1 | |
| SCHEMBL22991506 | 0.74 | POLB (0.35) | POLBNLRP3TOP1BACE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050010019-A1 | Diaminodicarboxylic acids and intermediates thereof | MITSUI CHEMICALS, INC. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1460058-A1 | DIAMINODICARBOXYLIC ACIDS AND INTERMEDIATES THEREOF | Mitsui Chemicals, Inc. (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-0828704-B1 | METHODS OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER LAMBERT CO (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5629447-A | Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| US-5616793-A | Methods of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010019-A1 | Diaminodicarboxylic acids and intermediates thereof | DDC, ODC1, ASS1 | POLB 2910/4885NLRP3 2285/4885TOP1 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.