Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005024 | 0.86 | TSHR (0.46) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL4925884 | 0.80 | HSD17B10 (0.41) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL48305 | 0.76 | HSD17B10 (0.86) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL25240603 | 0.71 | ERN1 (0.59) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL1275325 | 0.71 | LMNA (0.39) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29578395 | 0.71 | LMNA (0.39) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL592892 | 0.70 | HSD17B10 (0.75) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| Triclofenol SCHEMBL1338 | 0.70 | HSD17B10 (1.00) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| Triclofenol SCHEMBL29387498 | 0.70 | HSD17B10 (1.00) | TSHRHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9077264 | 0.70 | HSD17B10 (0.52) | HSD17B10HPGDCYP3A4CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170187060-A1 | INEXPENSIVE METAL-FREE ORGANIC REDOX FLOW BATTERY (ORBAT) FOR GRID-SCALE STORAGE | U.S. DEPARTMENT OF ENERGY | 2017-06-29 | — | — | US | disclosed |
| EP-0189773-A2 | Process for preparing composite articles from rubber and pourable polyurethane elastomers | RHEIN-CHEMIE RHEINAU GmbH (DE) | 1986-08-06 | — | — | EP | disclosed |