Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194796 | 0.87 | CA2 (0.46) | GAACTBP2ALDH1A1RAB9ALMNA | |
| Toluene SCHEMBL4236990 | 0.85 | SMN1; SMN2 (0.51) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL3501067 | 0.84 | NR4A2 (0.64) | — | |
| SCHEMBL28455325 | 0.80 | LMNA (0.54) | GAAALDH1A1LMNAHTTKMT2A | |
| SCHEMBL526194 | 0.80 | GAA (0.57) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL11185173 | 0.78 | GAA (0.55) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL76050 | 0.78 | NPC1 (0.53) | CTBP2TDP1POLBEGFRERBB2 | |
| SCHEMBL11510399 | 0.78 | CA2 (0.52) | GAACTBP2RAB9ALMNAHTT | |
| SCHEMBL6562633 | 0.78 | GAA (0.55) | GAACTBP2TDP1POLBAPEX1 | |
| SCHEMBL104746 | 0.78 | CA2 (0.62) | GAACTBP2TDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878515-A | Substituted aniline pyrimidine compound and preparation method and application thereof | 河北科技大学 | 2024-11-01 | — | — | CN | claimed |
| CN-117510429-A | Compound containing methyl isoxazole structure, and preparation method and application thereof | 中国农业大学 | 2024-02-06 | — | — | CN | claimed |
| CN-117024298-A | Tertiary amide compound containing naphthyl and its preparation method and application | 北京中医药大学 | 2023-11-10 | — | — | CN | claimed |
| CN-114805223-B | 2, 4-disubstituted quinazoline compound for inhibiting EGFR, preparation method and application | 自贡市第四人民医院(自贡市急救中心) | 2023-05-09 | — | — | CN | claimed |
| CN-115703737-A | Hydroxypyridones compounds and application thereof as antibiotic sensitizer for overcoming drug resistance of bacterial biofilm | 暨南大学 | 2023-02-17 | — | — | CN | claimed |
| CN-114805223-A | 2, 4-disubstituted quinazoline compound for inhibiting EGFR (epidermal growth factor receptor), and preparation method and application thereof | 自贡市第四人民医院(自贡市急救中心) | 2022-07-29 | — | — | CN | claimed |
| CN-114478307-A | Crosslinking agent containing double nitrogen groups and preparation method and application thereof | 苏州欧谱科显示科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-112441990-A | Bisamide compound containing 3, 4-dichloroisothiazole heterocycle, and preparation method and application thereof | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-112174869-A | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | claimed |
| US-8772493-B2 | Compounds having auditory protective effect | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2014-07-08 | — | — | US | claimed |
| CN-102617440-B | Method for preparing atorvastatin calcium | HUNAN OUYA BIOLOG CO LTD | 2013-11-06 | — | — | CN | claimed |
| US-8530465-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-09-10 | — | — | US | claimed |
| US-20130217881-A1 | NOVEL COMPOUNDS HAVING AUDITORY PROTECTIVE EFFECT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2013-08-22 | — | — | US | claimed |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | HUANG HSU-SHAN (TW) | 2013-03-07 | — | — | US | claimed |
| CN-102617440-A | Method for preparing atorvastatin calcium | HUNAN OUYA BIOLOG CO LTD | 2012-08-01 | — | — | CN | claimed |
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | claimed |
| US-6432953-B1 | — | — | None | — | — | US | disclosed |
| CN-122094834-A | Resin composition for three-dimensional printing | — | 2026-05-26 | — | — | CN | disclosed |
| US-3962254-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217881-A1 | NOVEL COMPOUNDS HAVING AUDITORY PROTECTIVE EFFECT | AIFM1, AIFM2, BAX | GAA 4679/4885CTBP2 1027/4885TDP1 1670/4885 |
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA1, ANXA5, ANXA2 | GAA 2160/4885CTBP2 3429/4885TDP1 4625/4885 |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA5, ANXA1, HCCS | GAA 1613/4885CTBP2 3454/4885TDP1 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.