Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819146 | 0.88 | ALDH1A1 (0.66) | TDP1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL1961876 | 0.83 | NPC1 (0.68) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7183238 | 0.82 | RAB9A (0.67) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL10489953 | 0.81 | ALDH1A1 (0.76) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7058035 | 0.81 | RAB9A (0.79) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL5667964 | 0.80 | NPC1 (0.51) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL5742618 | 0.76 | RAB9A (0.68) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL1579322 | 0.76 | MMP2 (0.48) | TDP1NPC1RAB9AHSD17B10MAPT | |
| SCHEMBL9976437 | 0.76 | NPC1 (0.71) | TDP1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7833293 | 0.76 | MMP2 (0.52) | NPC1RAB9AHSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065811-B1 | DISPERSE AZOPYRIMIDINE DYESTUFFS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-02 | — | — | EP | disclosed |
| US-4146535-A | Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
| US-3979378-A | Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |