Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885147 | 0.84 | L3MBTL1 (0.39) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10886910 | 0.76 | TAAR1 (0.38) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10883500 | 0.74 | TP53 (0.47) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10885162 | 0.73 | ADRA2C (0.51) | ADRA1A | |
| SCHEMBL2103783 | 0.71 | TAAR1 (0.46) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL223967 | 0.70 | TAAR1 (0.38) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8989302 | 0.69 | TAAR1 (0.37) | TAAR1HTR1D | |
| SCHEMBL8989374 | 0.69 | MAPT (0.38) | TAAR1HTR1D | |
| SCHEMBL224838 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL10883596 | 0.69 | KCNH2 (0.39) | TAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081324-B1 | SUBSTITUTED PHARMACOLOGICALLY ACITVE IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-08-06 | — | — | EP | disclosed |