Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5301134 | 0.77 | ALDH1A1 (0.52) | MAPK1ALDH1A1HPGDRECQLTSHR | |
| SCHEMBL2027355 | 0.74 | MAPK1 (0.69) | MAPK1ALDH1A1HPGDTSHRHTT | |
| SCHEMBL13946167 | 0.74 | DAO (0.64) | MAPK1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1110850 | 0.67 | GPR84 (0.53) | ALDH1A1HPGDTP53RECQLTSHR | |
| SCHEMBL13735717 | 0.66 | TP53 (0.69) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL23900415 | 0.65 | MAPK1 (0.56) | MAPK1ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL27658904 | 0.65 | MAPK1 (0.51) | MAPK1ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL11133098 | 0.65 | MEN1 (0.56) | ALDH1A1HPGDTP53RECQLTSHR | |
| SCHEMBL16297352 | 0.65 | TP53 (0.46) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL7378101 | 0.64 | CRHBP (0.50) | MAPK1ALDH1A1HPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61112059-A | — | — | None | — | — | JP | disclosed |
| JP-S61112059-A | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBONITRILE DERIVATIVE | MORISHITA SEIYAKU KK | 1986-05-30 | — | — | JP | disclosed |