SCHEMBL10883204

SCHEMBL10883204

O=C1C=CC(=O)N1c1ccc(-c2ccccc2)cc1S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.49
ATM Q13315 4/20 0.49
FAAH O00519 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HSP90AA1 P07900 3/20 0.49
HTT P42858 3/20 0.49
PKM P14618 2/20 0.49
TLR9 Q9NR96 3/20 0.43
NPSR1 Q6W5P4 3/20 0.40
MITF O75030 1/20 0.40
CCR6 P51684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTPN1 P18031 1/20 0.38
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
XBP1 P17861 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707910 0.79 TLR9 (0.59) MGLLATMFAAHALDH1A1HSP90AA1
SCHEMBL8536379 0.79 TLR9 (0.59) MGLLATMFAAHALDH1A1HSP90AA1
SCHEMBL28295804 0.79 MGLL (0.61) MGLLATMFAAHALDH1A1HSP90AA1
SCHEMBL28883324 0.73 TLR9 (0.47) MGLLATMFAAHALDH1A1HSP90AA1
SCHEMBL29094088 0.73 MGLL (0.64) MGLLATMFAAHALDH1A1HSP90AA1
SCHEMBL2848670 0.72 HTR6 (0.52)
SCHEMBL8367501 0.72 ALOX5 (0.55) ALDH1A1HSP90AA1HTTPTPN1MEN1
SCHEMBL5973210 0.70 IKBKB (0.51) ALDH1A1HSP90AA1HTTTDP1PTPN1
SCHEMBL4190433 0.70 ACLY (0.50) PTPN1
SCHEMBL4843096 0.70 MAOB (0.48) ATMHTTNPSR1PTPN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107316-B1 SODIUM STYRENE SULFONATE-CO-SODIUM-N-(4-SULFOPHENYL)-MALEIMIDE - AN IMPROVED VISCOSITY CONTROL ADDITIVE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-08-06 EP disclosed
US-4478727-A DRILLING MUDS FOR OIL AND GAS WELLS EXXON RESEARCH & ENGINEERING CO. (US) 1984-10-23 US disclosed
EP-0107316-A1 Sodium styrene sulfonate-co-sodium-N-(4-sulfophenyl)-maleimide - an improved viscosity control additive EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-05-02 EP disclosed