Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886790 | 0.92 | GPR84 (0.42) | PTGS2LMNAGPR84SMN1; SMN2NPSR1 | |
| SCHEMBL21638088 | 0.90 | HTT (0.38) | PTGS2TLR8MAPTSMN1; SMN2NPC1 | |
| SCHEMBL23966831 | 0.88 | MAPT (0.44) | PTGS2TLR8LMNAPKMGAA | |
| SCHEMBL202220 | 0.84 | PTGS2 (0.40) | PTGS2TLR8LMNAPKMGAA | |
| SCHEMBL10888125 | 0.82 | PTGS2 (0.39) | PTGS2TLR8LMNAPKMGAA | |
| SCHEMBL11048831 | 0.80 | HTT (0.36) | PTGS2MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10884085 | 0.79 | ALOX15 (0.41) | PTGS2TLR8LMNAPKMGAA | |
| SCHEMBL200260 | 0.78 | PTGS2 (0.53) | PTGS2TLR8LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10887277 | 0.77 | THRB (0.44) | PTGS2GPR84SMN1; SMN2 | |
| SCHEMBL11239493 | 0.77 | PTGS2 (0.36) | PTGS2TLR8LMNAPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122203-B1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORPORATION (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4533753-A | SULFIDING A PHENOL USING A DISULFIDE AND ALUMINUM PHENOXIDE CATALYST; OXIDATION RESISTANCE; OIL ADDITIVES | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| WO-1984004092-A1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORP (US) | 1984-10-25 | — | — | WO | disclosed |
| EP-0122203-A1 | (Hydrocarbylthio)phenols and their preparation | ETHYL CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |