Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638088 | 0.91 | HTT (0.38) | HTTMAPTSMN1; SMN2ALDH1A1TYR | |
| SCHEMBL4539436 | 0.82 | HTT (0.43) | HTTMAPTSMN1; SMN2ALDH1A1TYR | |
| SCHEMBL10885010 | 0.80 | PTGS2 (0.40) | HTTMAPTSMN1; SMN2NPC1MAPK1 | |
| SCHEMBL280118 | 0.78 | TYR (0.48) | HTTMAPTSMN1; SMN2ALDH1A1TYR | |
| SCHEMBL10886790 | 0.77 | GPR84 (0.42) | SMN1; SMN2TYRNPSR1PTGS2 | |
| SCHEMBL9745932 | 0.76 | ALOX5 (0.46) | HTTMAPTTYRALOX5PTGS2 | |
| SCHEMBL3821186 | 0.76 | ALOX5 (0.46) | HTTMAPTTYRALOX5PTGS2 | |
| SCHEMBL9746222 | 0.76 | ALOX5 (0.46) | HTTMAPTTYRALOX5PTGS2 | |
| SCHEMBL9745591 | 0.76 | ALOX5 (0.46) | HTTMAPTTYRALOX5PTGS2 | |
| SCHEMBL29112780 | 0.76 | TYR (0.47) | HTTMAPTSMN1; SMN2ALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060799-B1 | DIESTER ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-06-06 | — | — | EP | disclosed |
| US-4394476-A | POLYMERS, BUTADIENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0060799-A1 | Diester antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| US-4108831-A | FOR CONJUGATED DIENE POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-08-22 | — | — | US | disclosed |