Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202220 | 0.88 | PTGS2 (0.40) | MAPTPTGS2MAOAMAOBAR | |
| SCHEMBL10887277 | 0.84 | THRB (0.44) | PTGS2 | |
| SCHEMBL10886492 | 0.81 | SHBG (0.38) | TP53PTGS2MAOAMAOBPTGS1 | |
| SCHEMBL10690265 | 0.80 | MAPT (0.40) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL10693117 | 0.78 | MAPT (0.47) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL10886511 | 0.78 | ALOX15 (0.43) | TP53PTGS2ARPTGS1ALDH1A1 | |
| SCHEMBL10889062 | 0.78 | CYP2C19 (0.43) | MAPTTP53PTGS2PTGS1ALDH1A1 | |
| SCHEMBL10885328 | 0.77 | THRB (0.40) | PTGS2 | |
| SCHEMBL28763167 | 0.77 | THRB (0.43) | PTGS2 | |
| SCHEMBL10889134 | 0.77 | PTGS2 (0.33) | PTGS2MAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122203-B1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORPORATION (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4533753-A | SULFIDING A PHENOL USING A DISULFIDE AND ALUMINUM PHENOXIDE CATALYST; OXIDATION RESISTANCE; OIL ADDITIVES | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| WO-1984004092-A1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORP (US) | 1984-10-25 | — | — | WO | disclosed |
| EP-0122203-A1 | (Hydrocarbylthio)phenols and their preparation | ETHYL CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |