Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886511 | 0.89 | ALOX15 (0.43) | CYP2C19PTGS1PTGS2HIF1ANR5A2 | |
| SCHEMBL14773884 | 0.79 | CYP2C19 (0.43) | CYP2C19PTGS1PTGS2GABRA1GABRB2 | |
| SCHEMBL10888337 | 0.79 | KLF10 (0.46) | CYP2D6ALDH1A1MEN1GAAMAPT | |
| SCHEMBL10884085 | 0.78 | ALOX15 (0.41) | PTGS2HIF1ANR5A2NR5A1CYP3A4 | |
| SCHEMBL10885339 | 0.78 | MAPT (0.39) | PTGS1PTGS2TP53ALDH1A1MAPT | |
| SCHEMBL10886492 | 0.76 | SHBG (0.38) | PTGS1PTGS2TP53ALDH1A1HSPA5 | |
| SCHEMBL21865141 | 0.73 | ALDH1A1 (0.46) | CYP2C19PTGS2CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10887261 | 0.73 | GABRA1 (0.48) | CYP2C19PTGS1PTGS2GABRA1GABRB2 | |
| SCHEMBL10888990 | 0.72 | ALOX15 (0.46) | CYP2C19PTGS1PTGS2GABRA1GABRB2 | |
| SCHEMBL10888427 | 0.71 | SHBG (0.38) | PTGS2CYP2C9CYP2D6HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122203-B1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORPORATION (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4533753-A | SULFIDING A PHENOL USING A DISULFIDE AND ALUMINUM PHENOXIDE CATALYST; OXIDATION RESISTANCE; OIL ADDITIVES | ETHYL CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| WO-1984004092-A1 | (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION | ETHYL CORP (US) | 1984-10-25 | — | — | WO | disclosed |
| EP-0122203-A1 | (Hydrocarbylthio)phenols and their preparation | ETHYL CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |