Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287905 | 0.87 | ALDH1A1 (0.46) | MAPTALDH1A1CYP3A4HTTMEN1 | |
| SCHEMBL10766268 | 0.85 | TDP1 (0.42) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11411623 | 0.84 | MEN1 (0.38) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10947425 | 0.83 | GPR35 (0.39) | MAPTALDH1A1CYP3A4HTTMEN1 | |
| SCHEMBL9120594 | 0.81 | MEN1 (0.52) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL11190333 | 0.81 | TDP1 (0.43) | MAPTALDH1A1CYP3A4HTTMEN1 | |
| SCHEMBL11295140 | 0.80 | ALDH1A1 (0.33) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10430085 | 0.80 | TDP1 (0.43) | MAPTALDH1A1CYP3A4HTTMEN1 | |
| SCHEMBL11213666 | 0.79 | TDP1 (0.57) | MAPTALDH1A1CYP3A4HTTMEN1 | |
| SCHEMBL10608335 | 0.79 | KMT2A (0.36) | MAPTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186989-A2 | 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitro-alpha-substituted-acetophenone, oxime derivative thereof, process for preparing thereof, herbicidal composition, and method for the destruction of undesirable weeds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-07-09 | — | — | EP | disclosed |