Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.59 |
| ▸ | PARP1 known ✓ | P09874 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.95 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.95 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.95 |
| ▸ | PTGIR | P43119 | 1/20 | 0.75 |
| ▸ | NQO2 | P16083 | 2/20 | 0.68 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.64 |
| ▸ | F2 | P00734 | 2/20 | 0.64 |
| ▸ | PLAU | P00749 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.59 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.59 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428892 | 0.98 | PRSS1 (1.00) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL9852190 | 0.92 | PRSS1 (0.81) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL15293729 | 0.91 | PRSS1 (0.88) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL9852193 | 0.90 | PRSS1 (0.84) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL5788625 | 0.86 | PTGIR (1.00) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| Hydrochloric Acid SCHEMBL30859643 | 0.84 | ALDH1A1 (0.74) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL10890871 | 0.83 | PRSS1 (0.72) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| Hydrochloric Acid SCHEMBL31546705 | 0.82 | PRSS1 (0.66) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| SCHEMBL14599566 | 0.82 | NQO2 (1.00) | PRSS1PRSS2PRSS3PTGIRNQO2 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.80 | PRSS1 (0.78) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120166906-A | Two-dimensional/three-dimensional perovskite heterojunction based on amidino cation and application of perovskite heterojunction in solar cell | 西安交通大学 | 2025-06-17 | — | — | CN | claimed |
| CN-118086928-A | Method for electrochemical synthesis of pyrimidoindole derivative under mild condition | 湘潭大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117926289-A | Method for electrochemically synthesizing N-sulfoamidine derivatives under mild condition | 湘潭大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-116947854-A | Preparation method of imidazo [2,1-a ] isoquinoline compound | 赣南师范大学 | 2023-10-27 | — | — | CN | claimed |
| CN-114853681-A | Preparation method of pyrimidine heterocyclic guanyl formate compound | 南京工业大学 | 2022-08-05 | — | — | CN | claimed |
| CN-113024470-B | 4-perfluoroalkyl substituted pyrimidine compound and preparation method and application thereof | 南京工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113024470-A | 4-perfluoroalkyl substituted pyrimidine compound and preparation method and application thereof | 南京工业大学 | 2021-06-25 | — | — | CN | claimed |
| CN-112159411-A | Trifluoromethyl substituted pyrimido [1,3] diaza compound and preparation method thereof | 南京工业大学 | 2021-01-01 | — | — | CN | claimed |
| JP-7233154-A | — | — | None | — | — | JP | disclosed |
| JP-1319465-A | — | — | None | — | — | JP | disclosed |
| CN-120166906-A | Two-dimensional/three-dimensional perovskite heterojunction based on amidino cation and application of perovskite heterojunction in solar cell | 西安交通大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-118086928-A | Method for electrochemical synthesis of pyrimidoindole derivative under mild condition | 湘潭大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-117926289-A | Method for electrochemically synthesizing N-sulfoamidine derivatives under mild condition | 湘潭大学 | 2024-04-26 | — | — | CN | disclosed |
| US-4113868-A | 5,6-DIHYDROPYRIMIDIN-4(3H)ONE DERIVATIVES, AND ANTIEDEMA COMPOSITIONS AND METHODS EMPLOYING THEM | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1978-09-12 | — | — | US | disclosed |
| US-4093811-A | 2-Aryl-4-cyanomethyl-5-methylimidazoles | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-06-06 | — | — | US | disclosed |
| US-4026891-A | HYPOTENSIVE AGENTS, ANTITHROMBOTICS, AND CARDIOTONICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3968213-A | 4-HYDROXY-5-CARBOXY PYRIMIDINES | PFIZER INC. (US) | 1976-07-06 | — | — | US | disclosed |
| US-3957784-A | ANTIALLERGY AGENTS | PFIZER INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |