SCHEMBL10890971

SCHEMBL10890971

CCCCCS(=O)(=O)OC(=O)CN

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.39
CA2 P00918 5/20 0.38
FAAH O00519 5/20 0.38
CA9 Q16790 3/20 0.38
CA12 O43570 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CA7 P43166 1/20 0.38
CES2 O00748 6/20 0.37
CES1 P23141 5/20 0.37
CA1 P00915 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28072084 0.98 CA2 (0.41) HTR2CCA2FAAHCA9CA12
SCHEMBL7432142 0.84 NAAA (0.45) CA2FAAHCA9CA12CA14
SCHEMBL32679584 0.84 CES2 (0.44) CA2FAAHCA9CA12CA14
SCHEMBL6578152 0.84 CES2 (0.41) HTR2CCA2FAAHCA9CA12
SCHEMBL4621658 0.82 CES2 (0.46) CA2FAAHCA9CA12CA14
SCHEMBL8364456 0.82 NAAA (0.48) CA2FAAHCA9CA12CA14
SCHEMBL9094766 0.82 CES2 (0.46) CA2FAAHCA9CA12CA14
SCHEMBL9095001 0.82 CES2 (0.46) CA2FAAHCA9CA12CA14
SCHEMBL9097583 0.82 CES2 (0.46) CA2FAAHCA9CA12CA14
SCHEMBL9095203 0.82 CES2 (0.46) CA2FAAHCA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4632931-A ANTICOAGULANTS, BRONCHODILATOR AGENTS E. R. SQUIBB & SONS, INC. (US) 1986-12-30 US disclosed