Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892079 | 0.88 | SLC27A1 (0.35) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10887197 | 0.88 | MEN1 (0.37) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10891764 | 0.86 | MEN1 (0.45) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10894037 | 0.84 | MAPT (0.35) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10890556 | 0.82 | MAPT (0.40) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10890976 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10894284 | 0.65 | DRD3 (0.33) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL11185641 | 0.65 | MAPT (0.47) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13387645 | 0.64 | PDK1 (0.36) | ALDH1A1MAPTNPC1RAB9ATDP1 | |
| Evandamine SCHEMBL6009808 | 0.64 | APOBEC3A (0.42) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600722-A | 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines and a process for the treatment of inflammatory or allergic processes in humans | A. NATTERMANN & CIE GMBH (DE) | 1986-07-15 | — | — | US | disclosed |
| EP-0155523-A1 | 3-Amino-1-(4,5,6,7-Tetrahydro-benzothiazolyl)-2-Pyrazolines,a process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-25 | — | — | EP | disclosed |