Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 13/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889054 | 0.84 | METAP2 (0.45) | METAP2L3MBTL3MAPTALDH1A1APAF1 | |
| SCHEMBL10887855 | 0.82 | ALDH1A1 (0.38) | METAP2MAPTALDH1A1 | |
| SCHEMBL10892360 | 0.81 | ALDH1A1 (0.45) | METAP2MAPTALDH1A1RAB9A | |
| SCHEMBL10893997 | 0.78 | ALDH1A1 (0.40) | METAP2MAPTALDH1A1 | |
| SCHEMBL10895233 | 0.78 | MAPT (0.45) | MAPTALDH1A1TDP1CACNA1BAPBA1 | |
| SCHEMBL10895262 | 0.76 | L3MBTL3 (0.50) | METAP2L3MBTL3ALDH1A1PDK1PDK2 | |
| SCHEMBL11013279 | 0.74 | L3MBTL3 (0.49) | METAP2L3MBTL3MAPTALDH1A1APP | |
| SCHEMBL10894580 | 0.74 | CHEK1 (0.45) | METAP2MAPTALDH1A1APP | |
| SCHEMBL10893396 | 0.73 | L3MBTL3 (0.46) | METAP2L3MBTL3ALDH1A1PDK1PDK2 | |
| SCHEMBL10891736 | 0.72 | SMN1; SMN2 (0.47) | METAP2MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |