Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10635283 | 0.79 | RAPGEF4 (0.44) | MAPTALDH1A1TDP1KDM4ERAPGEF4 | |
| SCHEMBL10894909 | 0.78 | METAP2 (0.43) | MAPTALDH1A1TDP1CACNA1BAPBA1 | |
| SCHEMBL10892360 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL10126981 | 0.72 | MAPT (0.54) | MAPTALDH1A1TDP1KDM4ERAD52 | |
| SCHEMBL343355 | 0.70 | RAPGEF4 (0.65) | MAPTALDH1A1TDP1KDM4ERAPGEF4 | |
| SCHEMBL10902421 | 0.69 | KMT2A (0.53) | TDP1POLBKMT2ANPSR1 | |
| SCHEMBL15486496 | 0.67 | MAPT (0.58) | MAPTALDH1A1TDP1KDM4ERAD52 | |
| SCHEMBL10893997 | 0.66 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL10892420 | 0.66 | CYP2C9 (0.47) | ALDH1A1RAPGEF4POLBGAAKMT2A | |
| SCHEMBL28284693 | 0.66 | CA1 (0.53) | ALDH1A1TDP1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |