SCHEMBL10895652

SCHEMBL10895652

Nc1cc(Cl)c(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
PRMT1 Q99873 2/20 0.44
SOS1 Q07889 1/20 0.43
PTGS2 P35354 2/20 0.43
PTGS1 P23219 1/20 0.43
CYP2C9 P11712 2/20 0.41
LMNA P02545 1/20 0.41
MPO P05164 1/20 0.41
TSHR P16473 1/20 0.41
HTR6 P50406 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.41
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683631 0.87 MAOA (0.59) KMT2AMEN1ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL15904417 0.83 PTGS2 (0.49) SOS1PTGS2PTGS1
SCHEMBL10898784 0.81 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL14458253 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL10708112 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL809432 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL10396881 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL822784 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL4374736 0.79 ALDH1A1 (0.73) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL2808226 0.78 MEN1 (0.50) KMT2AMEN1ALDH1A1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602109-A Novel pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for preparation UNION CARBIDE CORPORATION (US) 1986-07-22 US disclosed
EP-0113247-B1 PESTICIDAL PHENOXYPHENYL AND PHENOXYPYRIDYL BENZOYL UREAS AND PROCESS FOR THEIR PREPARATION UNION CARBIDE CORPORATION (US) 1986-06-11 EP disclosed
US-4540578-A Pesticidal phenoxypyridyl benzoyl ureas UNION CARBIDE CORPORATION (US) 1985-09-10 US disclosed
EP-0113247-A1 Pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for their preparation UNION CARBIDE CORPORATION (US) 1984-07-11 EP disclosed