SCHEMBL10897429

SCHEMBL10897429

C[Si](C)(C)C(F)(C(N)=O)[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2524372 0.72
SCHEMBL347228 0.72
SCHEMBL8769898 0.69 LMNA (0.35) LMNAALOX15BLMPMP22
SCHEMBL29253962 0.69
SCHEMBL435447 0.67
Trifluoroacetamide SCHEMBL7739632 0.67
Trifluoroacetamide SCHEMBL27598858 0.67
SCHEMBL622355 0.67
SCHEMBL17065142 0.67 LMNA (0.33) LMNAALOX15BLMPMP22
SCHEMBL10797506 0.67 LMNA (0.33) LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4609749-A Method for the simultaneous preparation of carboxylic acid trimethylsilyl esters and silylated carboxylic acid amides DYNAMIT NOBEL AG (DE) 1986-09-02 US disclosed