SCHEMBL10897516

SCHEMBL10897516

C=Cc1ccsc1Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.39
PTPN1 P18031 1/20 0.35
LTA4H P09960 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
LTB4R Q15722 4/20 0.32
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
GSTO1 P78417 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
MAOB P27338 1/20 0.31
BCL2 P10415 1/20 0.31
BCL2L1 Q07817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28044971 0.75 CALM1 (0.37) CALM1PTPN1L3MBTL1ALDH1A1LTB4R
SCHEMBL19222446 0.72 CYP2A6 (0.38) TSHR
SCHEMBL371748 0.72 CALM1 (0.46) CALM1PTPN1LTB4RBCL2BCL2L1
SCHEMBL20408063 0.71 TAAR1 (0.36) ALDH1A1
SCHEMBL6947065 0.71 ADRA1D (0.46) CALM1PTPN1ALDH1A1
SCHEMBL9024878 0.71 CALM1 (0.44) CALM1PTPN1LTA4HALDH1A1LTB4R
SCHEMBL31564493 0.70 KDM4E (0.38) ALDH1A1LTB4R
SCHEMBL163961 0.68 CALM1 (0.46) CALM1ALDH1A1TSHRBCL2BCL2L1
SCHEMBL10791795 0.68 CALM1 (0.46) CALM1LTA4HL3MBTL1ALDH1A1TSHR
SCHEMBL5109182 0.68 TSHR (0.43) CALM1PTPN1TSHRLTB4RPLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4567024-A SHIELDING LAYER FOR ERYTHROCYTES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-28 US disclosed
US-4551307-A FIBROUS DEVELOPING LAYER CONTAINING INTERACTIVE COMPOSITION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-05 US disclosed
US-4430436-A QUALITATIVE ANALYSIS; IMMUNOASSAY; HEAT-RESISTANT POLYMER PARTICLES FORMING A THREE-DIMENSIGNAL LATTICE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-02-07 US disclosed
US-4427632-A LIGHT TRANSMISSIVE SUPPORT, REAGENT LAYER, DEVELOPING LAYER FORMED BY COATING REAGENT LAYER WITH MACROMOLECULAR POLYMER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US disclosed