Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306828 | 0.80 | ALDH1A1 (0.47) | ADRA1DALOX5ALDH1A1MAPTHPGD | |
| SCHEMBL12425696 | 0.78 | TAAR1 (0.45) | ADRA1DALDH1A1 | |
| SCHEMBL371748 | 0.77 | CALM1 (0.46) | CALM1ALOX5HPGDALOX15HSD17B10 | |
| SCHEMBL9024878 | 0.75 | CALM1 (0.44) | CALM1ALOX5ALDH1A1MAPTUSP2 | |
| SCHEMBL28408319 | 0.75 | SLC6A2 (0.39) | CALM1ALDH1A1MAPTUSP2HPGD | |
| SCHEMBL15055602 | 0.75 | KEAP1 (0.56) | ADRA1DCALM1ALDH1A1MAPTUSP2 | |
| SCHEMBL6346971 | 0.73 | ADRA1D (0.45) | ADRA1DALOX5ALDH1A1HPGDLMNA | |
| SCHEMBL22624586 | 0.73 | ADRA1D (0.45) | ADRA1DCALM1ALDH1A1MAPTUSP2 | |
| Ethylamine SCHEMBL10586929 | 0.73 | ADRA1D (0.39) | ADRA1DALOX5ALDH1A1HPGDRECQL | |
| Ethylamine SCHEMBL10588624 | 0.72 | RAPGEF4 (0.36) | ADRA1DALOX5ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218739-A4 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-04 | — | — | EP | claimed |
| US-6458789-B1 | ANTICOAGULENTS, ANTIHISTAMINES, ANTISEPTICS, ANTIARRHYTHMICS AND ANTIRHEUMATICS | LION BIOSCIENCE AG (DE) | 2002-10-01 | — | — | US | claimed |
| EP-1218739-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023887-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | claimed |
| CN-110403005-A | The food materials anti-metamorphic protection liquid and its preparation method of herbal medicine fruits and vegetables | QUANRAN YINCHUAN TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |
| CN-110261555-A | The herb medicines such as Radix Astragali semen coicis matter data information detector and method | 权冉(银川)科技有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109781668-A | Sensor material and data informatization detection for quality of medicinal materials, fruits and vegetables | 权冉(银川)科技有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109781719-A | A kind of kit detecting trypsase and its inhibitor based on platinum cluster | 福建医科大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109164099-A | A method of detection indoor formaldehyde content | 张垚 | 2019-01-08 | — | — | CN | disclosed |
| CN-108395423-A | The synthetic method of 2- benzal tetrahydrothiophene derivatives | 苏州大学张家港工业技术研究院 | 2018-08-14 | — | — | CN | disclosed |
| CN-102977036-B | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | 美国陶氏益农公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-102731381-B | The polysubstituted aryl of 6-()-4-aminopyridine formic acid esters and the purposes as herbicide thereof | 美国陶氏益农公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102271516-A | Stable insecticide compositions and methods for producing same | — | 2011-12-07 | — | — | CN | disclosed |
| CN-101478877-A | Method for controlling insects resistant to common insecticides | DOW AGROSCIENCES LLC (US) | 2009-07-08 | — | — | CN | disclosed |
| CN-101384552-A | Insecticidal N-substituted (6-haloalkylpyridin-3-yl) alkylsulfinimides | DOW AGROSCIENCES LLC (US) | 2009-03-11 | — | — | CN | disclosed |
| EP-1218739-A4 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-04 | — | — | EP | disclosed |
| US-6458789-B1 | ANTICOAGULENTS, ANTIHISTAMINES, ANTISEPTICS, ANTIARRHYTHMICS AND ANTIRHEUMATICS | LION BIOSCIENCE AG (DE) | 2002-10-01 | — | — | US | disclosed |
| EP-1218739-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023887-A1 | 2-AMINOPYRIDINE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | disclosed |