Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905719 | 0.90 | DRD2 (0.52) | HTR2A | |
| SCHEMBL10896514 | 0.89 | DRD2 (0.62) | — | |
| SCHEMBL11245921 | 0.85 | — | — | |
| SCHEMBL11249894 | 0.84 | HTR7 (0.46) | — | |
| SCHEMBL11244508 | 0.84 | HTR2A (0.52) | HTR2ADRD3 | |
| SCHEMBL11249964 | 0.82 | HTR1A (0.51) | HTR2A | |
| Hydrochloric Acid SCHEMBL10896178 | 0.82 | HTR1A (0.50) | HTR2A | |
| SCHEMBL11163898 | 0.79 | USP2 (0.61) | HTR2ADRD3 | |
| SCHEMBL10895298 | 0.78 | DRD2 (0.51) | DRD3 | |
| Bromide SCHEMBL10898200 | 0.78 | USP2 (0.60) | HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | claimed |
| EP-0079564-B1 | 3-(1-SUBSTITUTED-4-PIPERIDYL)-1,2-BENZISOXAZOLES, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-03-19 | — | — | EP | disclosed |
| EP-0079564-A1 | 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles, a process for the preparation thereof, a pharmaceutical composition comprising the same, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | disclosed |