Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10896514 | 0.93 | DRD2 (0.62) | — | |
| SCHEMBL10905719 | 0.90 | DRD2 (0.52) | HTR2A | |
| SCHEMBL11249894 | 0.89 | HTR7 (0.46) | — | |
| SCHEMBL11249964 | 0.88 | HTR1A (0.51) | HTR2A | |
| Hydrochloric Acid SCHEMBL10896178 | 0.87 | HTR1A (0.50) | HTR2A | |
| SCHEMBL11245921 | 0.85 | — | — | |
| SCHEMBL10898652 | 0.84 | HTR2A (0.50) | HTR2ADRD3 | |
| SCHEMBL10898282 | 0.79 | P2RX7 (0.52) | HTR2A | |
| SCHEMBL11154995 | 0.76 | ACHE (0.67) | — | |
| SCHEMBL22048381 | 0.75 | ACHE (0.65) | HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | claimed |
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | disclosed |