Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060569 | 0.80 | DYRK1A (0.56) | KMT2AMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL7992784 | 0.76 | ALDH1A1 (0.51) | KMT2AMAPTGAAMAPK1TDP1 | |
| SCHEMBL10898779 | 0.74 | KMT2A (0.55) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL9197955 | 0.70 | SIRT1 (0.74) | KMT2A | |
| SCHEMBL9197946 | 0.70 | KMT2A (1.00) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL31432748 | 0.69 | MAPT (0.59) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL11179302 | 0.68 | NR1I2 (0.64) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL29516593 | 0.68 | KMT2A (0.76) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL28722336 | 0.68 | KMT2A (0.76) | KMT2AMAPTLMNAPLIN1GAA | |
| SCHEMBL9246152 | 0.68 | KMT2A (0.72) | KMT2AMAPTLMNAPLIN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258963-B1 | DRUGS, COSMETICS | HAARMANN & REIMER GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-1008593-A1 | Benzylidene-gamma-butyrolactones, process for their production and use thereof as UV absorbers | HAARMANN & REIMER GMBH (DE) | 2000-06-14 | — | — | EP | disclosed |