Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901966 | 0.88 | HTR2C (0.44) | HTR2CPLGSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10902522 | 0.82 | CDC7 (0.40) | PLGSLC6A4GABRA1GABRG2GABRB3 | |
| SCHEMBL10902292 | 0.82 | MPO (0.41) | SLC6A2SLC6A4SLC6A3HTR1ABCHE | |
| SCHEMBL10901738 | 0.82 | NPC1 (0.42) | SLC6A2SLC6A4SLC6A3HTR1AGABRA1 | |
| SCHEMBL2874838 | 0.81 | PLG (0.38) | HTR2CPLGGABRA1GABRG2GABRB3 | |
| SCHEMBL3891711 | 0.81 | HTR2C (0.48) | HTR2CHTR1AMEN1KMT2A | |
| SCHEMBL10902493 | 0.81 | CHRM2 (0.37) | PLGCYP2D6 | |
| Hydrochloric Acid SCHEMBL10321362 | 0.80 | HTR2C (0.39) | HTR2CPLGGABRA1GABRG2GABRB3 | |
| SCHEMBL10898355 | 0.78 | HTR2C (0.49) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL10901664 | 0.78 | QDPR (0.42) | HTR2CSLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | claimed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |