Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.39 |
| ▸ | DRD5 | P21918 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902292 | 0.81 | MPO (0.41) | HTR1ASLC6A2SLC6A3SLC6A4HTR2A | |
| SCHEMBL10901822 | 0.81 | P2RY14 (0.41) | HTR2CP2RY14SIGMAR1HTR2A | |
| SCHEMBL10901738 | 0.78 | NPC1 (0.42) | HTR1ASLC6A2SLC6A3SLC6A4KMT2A | |
| SCHEMBL10902855 | 0.78 | HTR2C (0.44) | HTR2CHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10902522 | 0.78 | CDC7 (0.40) | SIGMAR1SLC6A4 | |
| SCHEMBL9315695 | 0.76 | MTNR1A (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3891711 | 0.75 | HTR2C (0.48) | HTR2CHTR1AMEN1KMT2AHTR1B | |
| SCHEMBL10901664 | 0.75 | QDPR (0.42) | HTR2CSIGMAR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3509594 | 0.74 | GABRA1 (0.48) | HTR2CSIGMAR1ADRB2HTR2A | |
| SCHEMBL30735591 | 0.73 | HTR2C (0.56) | HTR2CP2RY14MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |