Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902855 | 0.82 | HTR2C (0.44) | SLC6A4SLC6A2SLC6A3HTR1ABCHE | |
| SCHEMBL10901738 | 0.82 | NPC1 (0.42) | SLC6A4SLC6A2SLC6A3HTR1AKCNH2 | |
| SCHEMBL10902522 | 0.82 | CDC7 (0.40) | SLC6A4BCHEACHE | |
| SCHEMBL10898355 | 0.81 | HTR2C (0.49) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL10902920 | 0.79 | DRD2 (0.40) | SLC6A4TNKSTNKS2ACHE | |
| SCHEMBL3891711 | 0.78 | HTR2C (0.48) | HTR1AHTR6 | |
| SCHEMBL10901664 | 0.78 | QDPR (0.42) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL3509594 | 0.78 | GABRA1 (0.48) | KCNH2BCHEACHEHTR2A | |
| SCHEMBL2874838 | 0.75 | PLG (0.38) | BCHEACHE | |
| SCHEMBL9202054 | 0.74 | MTNR1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | claimed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |