Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903614 | 0.84 | LMNA (0.40) | LMNASLC22A6TSHRHDAC11CYP1A2 | |
| SCHEMBL10907540 | 0.78 | ALDH1A1 (0.36) | LMNASLC22A6TSHRPHF8KDM2A | |
| SCHEMBL10903599 | 0.78 | LMNA (0.42) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL10903601 | 0.74 | CAMK2A (0.44) | LMNASLC22A6TSHRPHF8KDM2A | |
| SCHEMBL10905757 | 0.74 | AKR1B1 (0.46) | SLC22A6TSHRHDAC11KMT2AHDAC3 | |
| SCHEMBL10906197 | 0.73 | KDM4C (0.38) | LMNASLC22A6TSHRPHF8KDM2A | |
| SCHEMBL10906138 | 0.73 | TSHR (0.45) | LMNASLC22A6TSHRKMT2APHF8 | |
| SCHEMBL10906590 | 0.72 | LMNA (0.46) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL10903589 | 0.72 | ABCC4 (0.38) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL10906605 | 0.72 | AKR1B1 (0.59) | SLC22A6TSHRHDAC11KMT2APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |