Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906136 | 0.96 | LTA4H (0.45) | LTA4HPPARAHDAC2HDAC8HDAC6 | |
| SCHEMBL10905444 | 0.82 | KMT2A (0.46) | L3MBTL1ABATGAAMAPTHTT | |
| SCHEMBL10905465 | 0.81 | LTA4H (0.50) | LTA4HPPARAICMTALBL3MBTL1 | |
| SCHEMBL10906612 | 0.75 | HDAC6 (0.50) | PPARAHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL10905605 | 0.74 | LMNA (0.59) | GAAMAPTHTT | |
| SCHEMBL10903598 | 0.74 | TSHR (0.42) | GAAMAPTKDM4AKDM4C | |
| SCHEMBL10905765 | 0.74 | HDAC8 (0.46) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL10907540 | 0.72 | ALDH1A1 (0.36) | KDM4AKDM4C | |
| SCHEMBL10905453 | 0.71 | MTOR (0.40) | GAAMAPT | |
| SCHEMBL10906601 | 0.71 | GAA (0.49) | HDAC2HDAC8HDAC6HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |