Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340304 | 0.93 | CA12 (0.41) | LMNAPOLBHSD17B10RAB9ATSHR | |
| SCHEMBL10909172 | 0.87 | LMNA (0.43) | LMNAPOLBMAPTHSD17B10RAB9A | |
| SCHEMBL10908768 | 0.84 | PPARG (0.41) | LMNAPOLBMAPTHSD17B10RAB9A | |
| SCHEMBL10909636 | 0.83 | BRAF (0.41) | LMNAPOLBMAPTHSD17B10RAB9A | |
| SCHEMBL10909707 | 0.82 | CD40 (0.45) | POLBMAPTKMT2AHPGDMEN1 | |
| SCHEMBL10907651 | 0.81 | NPC1 (0.45) | HSD17B10RAB9AKCNMA1KMT2AALDH1A1 | |
| SCHEMBL11338535 | 0.80 | TRPV1 (0.46) | LMNAPOLBMAPTHSD17B10RAB9A | |
| SCHEMBL10905295 | 0.80 | PPARG (0.41) | LMNAPOLBMAPTHSD17B10RAB9A | |
| SCHEMBL10909173 | 0.79 | LMNA (0.41) | LMNAPOLBMAPTMAOBPPARG | |
| SCHEMBL10908002 | 0.79 | DHODH (0.43) | LMNAPOLBMAPTRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |