Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906611 | 0.68 | KMT2A (0.44) | KMT2ATSHRHDAC1HDAC6 | |
| SCHEMBL10907616 | 0.68 | KMT2A (0.44) | KMT2ATSHRMEN1HDAC1HDAC6 | |
| SCHEMBL12373434 | 0.67 | CPA1 (0.50) | MAOBABCB1 | |
| SCHEMBL11058157 | 0.67 | MAOB (0.48) | MAOBKCNA5ABCB1 | |
| SCHEMBL12473253 | 0.67 | KCNA5 (0.65) | KCNA5KMT2ATSHRPOLB | |
| SCHEMBL10906191 | 0.66 | HSD11B1 (0.42) | KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL12268202 | 0.66 | ALDH1A1 (0.61) | KCNA5KMT2AMEN1POLB | |
| SCHEMBL1811811 | 0.66 | ALDH1A1 (0.61) | KCNA5KMT2AMEN1POLB | |
| SCHEMBL22076551 | 0.66 | KMT2A (0.49) | KCNA5KMT2AABCB1TSHRAKT1 | |
| SCHEMBL8535929 | 0.66 | KCNA5 (0.49) | KCNA5KMT2ATSHRAKT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |