Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440869 | 0.92 | HPSE (0.42) | HPSEMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10907766 | 0.88 | ALDH1A1 (0.43) | HPSEMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11344516 | 0.88 | TRPV1 (0.49) | HPSEMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11428049 | 0.84 | MEN1 (0.41) | MAPTMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL11440904 | 0.84 | HSD17B10 (0.52) | HPSEMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11426294 | 0.84 | CASP6 (0.51) | MAPTMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL11433673 | 0.83 | HPGD (0.52) | MAPTMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL11435238 | 0.83 | AURKA (0.44) | HPSEMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11426181 | 0.83 | LMNA (0.47) | MAPTMEN1KMT2AHSD17B10TRPV1 | |
| SCHEMBL11441468 | 0.83 | AURKA (0.50) | HPSEMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |