Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423367 | 0.93 | HPGD (0.61) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11442387 | 0.86 | MEN1 (0.53) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL10907766 | 0.84 | ALDH1A1 (0.43) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11344516 | 0.84 | TRPV1 (0.49) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11433674 | 0.84 | KCNMA1 (0.54) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11430403 | 0.84 | MEN1 (0.51) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11426564 | 0.84 | HPGD (0.55) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11421978 | 0.84 | MEN1 (0.52) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11426177 | 0.83 | HPSE (0.42) | HPGDMAPTMEN1KMT2ALMNA | |
| SCHEMBL11442222 | 0.83 | RAB9A (0.59) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |