Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 2/20 | 0.43 |
| ▸ | CD40LG | P29965 | 2/20 | 0.43 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343025 | 0.93 | TIMP3 (0.48) | CD40CD40LGTIMP3FGF1CA2 | |
| SCHEMBL10909111 | 0.89 | KMT2A (0.47) | TIMP3MEN1KMT2ANPC1TP53 | |
| SCHEMBL11426294 | 0.88 | CASP6 (0.51) | CD40CD40LGCA2CA1CASP6 | |
| SCHEMBL10907766 | 0.85 | ALDH1A1 (0.43) | TIMP3MEN1KMT2ANPC1TP53 | |
| SCHEMBL11422937 | 0.83 | NPC1 (0.58) | CD40CD40LGCASP6CTDSP1MEN1 | |
| SCHEMBL10909707 | 0.82 | CD40 (0.45) | CD40CD40LGTIMP3CA2CA1 | |
| SCHEMBL10909172 | 0.82 | LMNA (0.43) | TIMP3MEN1KMT2ANPC1TP53 | |
| SCHEMBL11339146 | 0.82 | RECQL (0.54) | TIMP3MEN1KMT2ATP53 | |
| SCHEMBL10909141 | 0.81 | CD40 (0.52) | CD40CD40LGTIMP3FGF1CA2 | |
| SCHEMBL10908823 | 0.81 | TIMP3 (0.52) | CD40CD40LGTIMP3FGF1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |